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Perenterol 250 is an antidiarrheal and contains a yeast fungus (Saccharomyces boulardii) as an active substance. It is used to treat diarrheal diseases such as traveler's diarrhea and, if prescribed by a doctor, for the prevention and treatment of antibiotic-related diarrhea or diarrhea caused by tube feeding; in conjunction with other measures, it allows the restoration of the intestinal flora and the alleviation of diarrhea.
Perenterol 250 regulates and normalizes intestinal activity.
The Saccharomyces boulardii yeast is resistant to antibiotics and acts in a living form inside the intestine. It is not absorbed by the body.
In various studies, an inhibiting effect on the development of various harmful bacteria and Candida albicans could be determined.
Swissmedic-approved patient information
Perenterol 250, sachets and capsulesZambon Switzerland LtdPerenterol 250 is a Antidiarrheal and contains a yeast fungus (Saccharomyces boulardii) as an active ingredient. It is used to treat diarrheal diseases such as traveler's diarrhea and, if prescribed by a doctor, for the prevention and treatment of antibiotic-related diarrhea or diarrhea caused by tube feeding; in conjunction with other measures, it allows the restoration of the intestinal flora and the alleviation of diarrhea.
Perenterol 250 regulates and normalizes intestinal activity.
The Saccharomyces boulardii yeast is resistant to antibiotics and acts in a living form inside the intestine. It is not absorbed by the body.
In various studies, an inhibiting effect on the development of various harmful bacteria and Candida albicans could be determined.
In the case of diarrhea, the patient (especially children and older people) should drink enough fluids. If the illness lasts longer than 2-3 days, the doctor should be consulted. In infants, diarrhea can quickly become dangerous after just one day due to the loss of fluid and salt. You should therefore consult your doctor in good time.
In the event of hypersensitivity to the preparation. Yeast allergy, especially to Saccharomyces boulardii.
Perenterol 250 must not be used in patients with severe immune deficiency (e.g. HIV infections, organ transplants, leukemia, malignant advanced tumors, radiation, chemotherapy, long-term high-dose cortisone treatment).
Patients with a central venous catheter (e.g. Port-A-cath) must not use Perenterol 250 because of the risk of infection with Saccharomyces boulardii.
Since Perenterol 250 consists of living cells, the preparation must not be heated with a too hot (over 50 °C) , ice-cold or alcoholic liquid or food.
Furthermore, the yeasts contained in Perenterol 250 are sensitive to antifungal drugs (antimycotics). If your doctor has prescribed such medicines for you, you must refrain from taking Perenterol 250 because its active substance will then be destroyed.
Tell your doctor, pharmacist or druggist if you
There are no objections to using Perenterol 250 during pregnancy or while breastfeeding.
The preparation is taken orally.
Initial dosage: take 2 sachets or 2 capsules (1 in the morning and 1 in the evening) on day 1.
Further dosing: on the following days: 1 sachet or 1 capsule daily until no more symptoms of the disease appear.
Upon medical advice, the initial dosage (2 sachets or 2 capsules daily) can be continued or increased over several days if necessary.
In case of vomiting within 1 hour after administration of the drug, the intake must be repeated.
Perenterol 250 can be administered to infants, children and adults in the same dosage.
sachet: mix the contents of the sachet with liquid or mushy food, then swallow. For infants: sprinkle the contents of the sachet over the pap or add to the bottle. Make sure that the food is not too hot (not over 50 °C).
Capsules: swallow the capsule with some liquid.
Perenterol 250 can be taken at any time of the day. If you want to achieve a rapid onset of action, you can take the preparation before meals.
You can also take Perenterol 250 with an antibiotic at any time, but not with an antifungal.
Follow the dosage given in this leaflet or as prescribed by your doctor. If you think the medicine is too weak or too strong, talk to your doctor, pharmacist or druggist.
In rare cases, flatulence occurs after taking Perenterol 250 and in very rare cases constipation. Very rarely, allergic skin reactions such as itching, skin rashes or hives, shortness of breath, anaphylactic reactions and anaphylactic shock can occur.
In very rare cases, penetration of the yeast fungus into the blood (fungaemia) and isolated cases of severe blood infections (sepsis) have been observed in seriously ill or immunocompromised patients or in patients with central venous catheters, which can also cause fever.
If you get any side effects, talk to your doctor, pharmacist or druggist. This also applies in particular to side effects that are not listed in this leaflet.
The medicinal product may only be used up to the date marked «EXP» on the container.
Do not store above 30 °C and keep out of the reach of children.
Your doctor, pharmacist or druggist can provide you with further information. These people have the detailed information for specialists.
250 mg Saccharomyces boulardii lyophilized (250 mg yeast), corresponding to at least 2 billion viable cells.
1 sachet contains: 32.5 mg lactose, vanillin, flavorings and additives.
1 capsule contains: 32.5 mg lactose and excipients.
47572, 47571 (Swissmedic).
In pharmacies and drugstores, without a doctor's prescription.
Packs of 10 and 20 sachets and packs of 6, 10 and 20 capsules.
Zambon Schweiz AG, 6814 Cadempino
This leaflet was last checked by the Medicines Agency (Swissmedic) in February 2021.