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The active ingredient in Duphalac is lactulose, a sugar that does not occur naturally.
Since your body cannot digest or absorb Duphalac, it remains in the intestine and reaches the large intestine unchanged. There it causes an increase in acidity due to the conversion by the intestinal flora. This stimulates the colon. A larger amount of water is also retained in the large intestine, which allows for softening of the stool and easier elimination. In addition, the transfer of certain toxic substances from the intestinal contents into the blood circulation is prevented and they are excreted with the stool.
Duphalac is taken for constipation, i.e. if you have problems emptying your stool. These difficulties can come in two forms: either no voiding at all, or then small and hard stools. Duphalac helps improve bowel movements. We also recommend that you adjust your daily habits as well. Below is some practical advice that may help you.
Lactulose, as a prebiotic substance, can enhance the growth of health-promoting bacteria (such as Bifidobacteria and Lactobacillus) while suppressing potential disease-causing bacteria (such as Clostridium and Escherichia coli).
This can result in a more favorable balance in the gut flora.
The doctor can also use Duphalac to treat other diseases ( especially for liver disease).
The following advice can help you break the bad habits that are a common cause of constipation:
15 ml of Duphalac syrup contain a maximum of 2.8 g absorbable carbohydrates.
In normal doses, Duphalac can also be taken by diabetics.
If you are hypersensitive to the active ingredient or any of the ingredients.
People who have been prescribed a galactose or lactose-free diet by their doctor should not take Duphalac.
If there is an intestinal obstruction other than simple constipation, or if there is a tear or risk of a tear in the digestive tract, Duphalac must not be used. If in doubt, ask your doctor.
If after a few days you notice that your stools are too watery, it is enough to reduce the recommended doses.
As a precautionary measure, you should consult your doctor before using any laxative in children under 6 years of age. The use of laxative in children should only be carried out exceptionally and under medical monitoring.
Patients with the rare hereditary galactosis intolerance, Lapp lactase deficiency, fructose intolerance or glucose galactose malabsorption should not take. lead to the water and electrolyte equilibrium.
Search your doctor or yoursConsult your doctor before starting treatment if you have painful abdominal pain of undetermined cause, so that this can be clarified.
Inform your doctor, pharmacist or druggist, or your doctor, pharmacist or druggist if you
If used as directed, it can be taken during pregnancy and breastfeeding.
As a precaution If possible, you should avoid taking medicines during pregnancy and breastfeeding or ask your doctor, pharmacist or druggist for advice.
The dosage of Duphalac depends on your age, the severity of the constipation and how long the constipation has lasted.
Duphalac can be taken undiluted or diluted in a warm or cold drink.
A single dose should be swallowed immediately and not remain in the mouth for a long time.
In the case of a single daily dose, these should be taken at the same time, e.g. during breakfast.
Duphalac can be taken as a single daily dose or in two divided doses.
The initial dose can be individually adjusted after an adequate treatment result has been achieved. It may take some time (2-3 days) for the treatment to take effect. If the effect is too strong (stools too liquid or too large), the daily dose must be reduced or, on the contrary, increased if the effect is too weak.
The table below clearly indicates the doses of Duphalac to be taken:
Initial dose/day(1st to 3rd day)
with prolonged use
Adults and adolescents from 14 years
15-45 ml
10-25 ml
Children (7-14 years)
15 ml
10 ml
Children (1-6 years)
5-10 ml
5-10 ml
Infants under 1 year
≤5 ml
≤5 ml
The dose can be measured exactly using the enclosed dosing cup (2.5 to 30 ml).
Keep to the dosage given in the package insert or prescribed by the doctor. If you think that the medicine is too weak or too strong, talk to your doctor, pharmacist or druggist.
The following side effects can occur when taking Duphalac:
Especially at the beginning of treatment, temporary flatulence may occur, which you should not worry about. They are a sign of the effectiveness of Duphalac.
During treatment, digestive disorders such as abdominal pain, nausea and vomiting, as well as, in the case of too high doses, diarrhea and disturbances in the water and electrolyte balance.
If you notice any side effects that are not described here, you should inform your doctor, pharmacist or pharmacist.
The Medicines may only be used by the date marked «EXP» on the container.
Store at room temperature (15-25 °C); Do not freeze syrup and protect from sunlight.
Keep medicines out of the reach of children!
Your doctor, pharmacist or druggist can provide you with further information. These people have the detailed technical information.
15 ml Duphalac syrup contain 10.01 g lactulose
None; however, sulphites and other sugars such as lactose, galactose and fructose may be present.
32894 (Swissmedic).
In pharmacies and drugstores, without a doctor's prescription:
Duphalac, syrup in bottles: 200 ml, 500 ml and bundle pack 12 × 500 ml
Mylan Pharma GmbH, 6312 Steinhausen
This leaflet was last revised in June 2018 checked by the drug authority (Swissmedic).