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Creon contains the active ingredient pancreatin with the enzymes important for the digestion of food (lipase, amylase and protease) in a concentrated form. These break down the fats, proteins and carbohydrates contained in the food into usable components.
On the instructions of the doctor, pharmacist or druggist, Creon can also be used to treat or supplement insufficient pancreatic function, i.e. in the event of a lack or absence of digestive enzymes, e.g. after acute pancreatitis at the beginning from resumption of food or artificial nutrition, chronic pancreatitis, cystic pancreatic fibrosis or after surgical interventions in the digestive tract.
Creon contains pancreatin in the form of so-called micropellets. These are filled into capsules, which dissolve in the stomach within a few minutes.
The digestive enzymes are only released from the micropellets in the small intestine and quickly break down fats, proteins and carbohydrates. The digestive products of the food can now be absorbed from the intestine, just like the natural process of digestion.
Swissmedic-approved patient information
Creon®Mylan Pharma GmbHContains Creon the active ingredient pancreatin with the enzymes important for the digestion of food (lipase, amylase and protease) in a concentrated form. These break down the fats, proteins and carbohydrates contained in the food into usable components.
On the instructions of the doctor, pharmacist or druggist, Creon can also be used to treat or supplement insufficient pancreatic function, i.e. in the event of a lack or absence of digestive enzymes, e.g. after acute pancreatitis at the beginning from resumption of food or artificial nutrition, chronic pancreatitis, cystic pancreatic fibrosis or after surgical interventions in the digestive tract.
Creon contains pancreatin in the form of so-called micropellets. These are filled into capsules, which dissolve in the stomach within a few minutes.
The digestive enzymes are only released from the micropellets in the small intestine and quickly break down fats, proteins and carbohydrates. The digestive products of the food can now be absorbed from the intestine, just like the natural process of digestion.
In order to support the treatment and to improve your well-being, you should divide your daily amount of food into several smaller meals (possibly snacks).
Adequate hydration must be ensured throughout the treatment.
If you are hypersensitive (allergic) to any of the ingredients of the drug.
Children with pancreatic cystic fibrosis who are receiving long-term treatment with pancreatic enzyme preparations should have regular check-ups in specialized centers .
Specific narrowing of the large intestine has been observed in some patients with mucoviscidosis (cystic fibrosis) during therapy with pancreatic enzyme preparations. These led to abdominal pain, vomiting and constipation and in some cases required surgery. If such symptoms occur, the preparation must be discontinued immediately and the doctor consulted immediately.
This medicinal product contains less than 1 mmol sodium (23 mg) per capsule, i.e. essentially 'sodium-free'. it is almost «sodium-free».
Tell your doctor, pharmacist or druggist if you
• suffer from other diseases,
• have allergies or
• Take other medicines (including those you bought yourself!) or use them externally!
If you are pregnant or planning to become pregnant, or if you are breastfeeding, you should only use Creon after consulting the take by the doctor.
The doctor will determine the correct dosage for you. The capsules are swallowed whole with sufficient liquid during or immediately after meals or snacks. For patients who have trouble swallowing capsules (e.g. small children or the elderly), the capsules can be opened and the contents either given to soft food (e.g. apple puree or yoghurt) - to avoid chewing - or the contents to acidic ones Drink liquid (e.g. apple, orange or pineapple juice).
Do not dissolve, crush or chew the capsule contents and do not mix with non-acidic food or liquid (e.g. milk or milk porridge) to avoid destroying the protective film of the micropellets. This could lead to premature release of the active substance, causing inflammation of the lining of the mouth and reducing the effectiveness of Creon.
Creon capsules or their contents should not be kept in the mouth.
Any reconstitution of the contents of the capsule with food or liquid should be taken immediately and not stored.
Stick to the dosage given in the package leaflet or as prescribed by your doctor. If you think that the medicine is too weak or too strong, talk to your doctor, pharmacist or druggist.
Creon should not be used if you are allergic to pork protein, but this is extremely rare.
The following side effects may occur when taking Creon:
Stomach pain.
Nausea, vomiting, constipation, gas, diarrhea.
Skin reactions.
Creon can also cause other serious allergic reactions, such as breathing problems or swollen lips.
The side effects do not necessarily have to be related to the drug, but can also be related to insufficient pancreatic function.
Specific narrowing of the colon has been observed in some patients with cystic fibrosis receiving high doses of pancreatic enzyme therapy. These led to abdominal pain, vomiting and constipation and in some cases required surgery. If such symptoms occur, the preparation must be discontinued immediately and the doctor consulted immediately.
If you get any side effects, talk to your doctor, pharmacist or druggist. This also applies in particular to side effects that are not listed in this leaflet.
The medicinal product may only be used up to the date marked on the container with « EXP:» designated date can be used.
Once the container has been opened, Creon capsules can be kept for 6 months.
Store at room temperature (15 - 25 °C).
Keep container tightly closed in order to protect from moisture.
Keep out of the reach of children.
Your doctor, pharmacist or druggist can provide you with further information. These people have the detailed information for specialists.
1 capsule of Creon 10'000 contains 135.0 - 165.0 as an active ingredient mg pancreatin with 10,000 units of lipase, 8,000 units of amylase and 600 units of protease according to Ph. Eur.
1 Creon 20'000 capsule contains as an active ingredient 270.0 - 330.0 mg pancreatin with 20'000 units of lipase, 16'000 units of amylase and 1'200 units of protease according to Ph. Eur..
1 Creon 25,000 capsule contains 270.0 - 330.0 mg of pancreatin with 25,000 units of lipase, 18,000 units of amylase and 1,000 units of protease as an active ingredient according to Ph. Eur..
1 Creon 35,000 capsule contains 378.0 - 462.0 mg of pancreatin with 35,000 units of lipase, 25,200 units of amylase and 1,400 units of protease as an active ingredient according to Ph. Eur..
Macrogol 4000, Hypromellose phthalate, cetyl alcohol, triethyl citrate, dimeticone 1000.
Capsule Shell: Gelatin, E172 (Yellow), E172 (Black), E172 (Red), E171, Sodium Lauryl Sulfate.
Macrogol 4000, hypromellose phthalate, cetyl alcohol, triethyl citrate, dimeticone 1000.
Capsule shell: gelatin, E172 (yellow), E172 (red), sodium lauryl sulfate.
38'219 (Swissmedic).
In pharmacies and drugstores without a doctor's prescription.
Creon 10'000 / 20'000 / 25'000 / 35'000: packs of 50 and 100 capsules.
Mylan Pharma GmbH, 6312 Steinhausen
This leaflet was last checked by the Medicines Agency (Swissmedic) in November 2022.
[Version 210 D]